College Football Odds and Picks October 22nd – Memphis vs UCF, Colorado State vs Utah State and Washington vs Arizona
Jimmy Lake

Washington coach Jimmy Lake, center, stands on the sideline during the second half of the team’s NCAA college football game against UCLA, Saturday, Oct. 16, 2021, in Seattle. UCLA won 24-17. (AP Photo/Ted S. Warren)

  • A trio of intriguing games are on the slate Friday, Oct. 22, with Memphis visiting UCF, Colorado State traveling to Utah State and Washington at Arizona
  • The Knights  are slight favorites at home, while the Huskies and Rams are favored on the road
  • Check out the odds for the games and key information about each matchup in the article below

Three Friday night games – one from the American Athletic Conference, another in the Mountain West and another in the Pac-12 – provide bettors with plenty of options ahead of Saturday’s Week 8 slate.

Memphis visits UCF at 7:00 pm ET as a one-point favorite. The game will be be on ESPN2. Then, it’s Colorado State at Utah State at 9:30 pm ET on CBS Sports Network, with the Rams as 3.5-point favorites. Washington kicks it off at Arizona at 10:30 pm ET to close things out on ESPN2. The Huskies are installed as 17.5-point favorites.

Memphis vs UCF Odds

Team Moneyline Spread Total
Memphis -105 +1 (-110) Over 63 (-110)
UCF -115 -1 (-110) Under 63 (-110)

All odds taken Oct. 19 at DraftKings

Henigan Showing Out

When the Memphis Tigers (4-3, 1-2 AAC) visit the UCF Knights (3-2, 1-2 AAC) on Friday night in Orlando, it could come down to which true freshman quarterback outplays the other one. Oddsmakers have the home team favored by a point.

The Tigers will have Dallas-area native Seth Henigan under center, while the Knights counter with Mikey Keene, who won a pair of Arizona state playing for Chandler High School.

Henigan is tearing it up, averaging 307.6 passing yards per game while throwing 16 touchdown passes.

He left Memphis’ last game, a victory over Navy, early as a precautionary measure with a hand injury. He should be good to go for Friday’s critical  conference tilt.

As for Keene, he’s averaging 142 yards passing per game and has thrown four touchdowns and four picks in the three outings he has started and finished this season in place of injured starter Dillon Gabriel.

But he has plenty of help. UCF’s top offensive players are  running backs Johnny Richardson (6.1 yards per carry) and Isaiah Bowser (six touchdowns) and wideouts Ryan O’Keefe (375 receiving yards) and Tennessee transfer Brandon Johnson. The Knights are coming off a 56-21 shellacking at Cincinnati last week.

UCF had beaten Memphis 13 straight times before last year, when the Tigers rallied to beat the Knights 50-49. I’m giving the Knights a slight edge in this spot because of their well-rounded offense and desire to put last week behind them.

Colorado State vs Utah State Odds

Team Moneyline Point Spread Over/Under Total
Colorado State -155 -3.5 (+100) Over 58 (-120)
Utah State +135 +3.5 (-120) Under 58 (+100)

Mountain Men

When the Colorado State Rams (3-3, 2-0 Mountain West) enter Maverick Stadium in Logan Friday to face the Utah State Aggies (4-2, 2-1 Mountain West), they will be a confident bunch. Steve Addazio’s club allowed just 69 yards of total offense to New Mexico in last week’s 36-7 win over the Lobos in Albuquerque – the second-best performance in program history.

That’s likely a big reason why the Rams are road favorites in this spot.

If Colorado State’s special teams can pitch a shutout – something the Rams weren’t able to do against New Mexico giving up a 63-yard punt return TD, they should be in good shape. But with Savon Scarver returning kicks, that’s easier said than done. Scarver is averaging 27.3 yards per return this year and tied the NCAA record with his seventh kickoff return this season for a score. He is one of only five players in FBS history to do that.

Plus, the Aggies are never out of any game. Utah State has trailed by double digits in all four of its wins this season, including coming from behind in the fourth quarter in all three of its road wins. USU scored the winning touchdown at Washington State with 13 seconds to play and the winning touchdown at UNLV with 35 seconds remaining in the game.

CSU won’t replicate the defensive effort put forth in its last game. But the Rams will do enough to cover and beat the Aggies on the road.

The pick: Colorado State -3.5 (+100)

Washington vs Arizona Odds

Team Moneyline Point Spread Over/Under Total
Washington -850 -17 (-110) Over 45 (-110)
Arizona +575 +17 (-110) Under 45 (-110)

Will Arizona Ever Win?

It’ll be a battle of two struggling teams when the Washington Huskies (2-4, 1-2 Pac-12) travel to Tucson to face the winless Arizona Wildcats (0-6, 0-3 Pac-12). Not surprisingly, UW is a large favorite in this spot.

Huskies redshirt freshman quarterback Dylan Morris has a 5-5 record in the 10 games of the Jimmy Lake era and a conference-high eight interceptions in 2021. He simply hasn’t been able to generate offense this season, with UW ranked 100th in scoring (23.5 points per game) in the FBS. The running game, hasn’t helped much – ranking 112th nationally at 111 yards per game.

If you think Washington is anemic on offense, Arizona is even worse. The Wildcats are tied for last nationally in scoring at 14 points per game and have failed to put up at least 20 points in nine straight outings.

Will Plummer, who started this season in a 21-19 home loss to FCS opponent Northern Arizona, will get the start Friday with the team’s top two quarterbacks — Jordan McCloud and Gunner Cruz — lost to season-ending injuries in the past two games.

Plummer has a penchant for trying to make big play, not unlike another Plummer did up the road in Tempe 25 years ago. But Will (no relation to Jake) is also inexperienced. Hoping to make him capitalize on mistakes is UW’s standout outside linebacker Zion Tupuola-Fetui – who made his season debut last week after returning from an Achilles’ injury.

While it’s tempting to go with UW in this spot (Arizona has lost 18 in a row, the longest active streak in the FBS), the under is the clear play for this one.

The pick: Under 45 (-110)

Author Image

Blair Johnson

Sports Writer


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